Monotone and near-monotone biochemical networks
نویسندگان
چکیده
منابع مشابه
Monotone and Near-Monotone Systems
This paper provides an expository introduction to monotone and nearmonotone biochemical network structures. Monotone systems respond in a predictable fashion to perturbations, and have very robust dynamical characteristics. This makes them reliable components of more complex networks, and suggests that natural biological systems may have evolved to be, if not monotone, at least close to monoton...
متن کاملMonotone and near-monotone network structure
This paper provides an expository introduction to monotone and near-monotone biochemical network structures. Monotone systems respond in a predictable fashion to perturbations, and have very robust dynamical characteristics. This makes them reliable components of more complex networks, and suggests that natural biological systems may have evolved to be, if not monotone, at least close to monoto...
متن کاملMonotone and near-monotone network structure (part II)
We next describe recent work on monotone input/output systems (“MIOS” from now on). Monotone i/o systems originated in the analysis of mitogen-activated protein kinase cascades and other cell signaling networks, but later proved useful in the study of a broad variety of other biological models. Their surprising breath of applicability notwithstanding, of course MIOS constitute a restricted clas...
متن کاملMonotone and near-monotone network structure (part I)
This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from signed network structure, associated to purely stoichiometric information and ignoring fluxes. In particular, monotone systems respond in a predictable fashion ...
متن کاملMonotone chemical reaction networks
We analyze certain chemical reaction networks and show that every solution converges to some steady state. The reaction kinetics are assumed to be monotone but otherwise arbitrary. When diffusion effects are taken into account, the conclusions remain unchanged. The main tools used in our analysis come from the theory of monotone dynamical systems. We review some of the features of this theory a...
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ژورنال
عنوان ژورنال: Systems and Synthetic Biology
سال: 2007
ISSN: 1872-5325,1872-5333
DOI: 10.1007/s11693-007-9005-9